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sw 1783  (ATCC)


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    ATCC sw 1783
    Sw 1783, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 252 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sw 1783/product/ATCC
    Average 95 stars, based on 252 article reviews
    sw 1783 - by Bioz Stars, 2026-05
    95/100 stars

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    Transcription of p62/SQSTM1 is repressed by KMT5a and p53 in glioblastoma cell lines. A-B Quantitative RT-PCR analysis of p62/SQSTM1 , KMT5a , and PHF8 mRNA expression in SW1088 ( A ) or U87MG ( B ) cells, either non-treated (NT) or treated with UNC0379. C Quantitative RT-PCR analysis of p62/SQSTM1 and p53 mRNA levels in U251 cells not transfected, non-treated (NT) or treated with UNC0379, and in U251 cells transfected with a plasmid encoding wild type p53 (pcDNA p53WT), treated or not with UNC0379. D Quantitative RT-PCR analysis of p62/SQSTM1 and p53 mRNA levels in U87MG cells not transfected, non-treated (NT) or treated with UNC0379, and in U87MG cells transfected with a plasmid encoding mutant p53 (pcDNA p53mut), treated or not with UNC0379. Statistical analysis was performed using Student’s t-test or ANOVA. *p < 0.05; **p < 0.005; ***p < 0.0005; ****p < 0.00005. Dots represent biological replicates of independent experiments

    Journal: Cell Communication and Signaling : CCS

    Article Title: The lysine methyltransferase KMT5a and p53 regulate the expression of the key autophagy adaptor p62/SQSTM1 in glioblastoma

    doi: 10.1186/s12964-026-02665-x

    Figure Lengend Snippet: Transcription of p62/SQSTM1 is repressed by KMT5a and p53 in glioblastoma cell lines. A-B Quantitative RT-PCR analysis of p62/SQSTM1 , KMT5a , and PHF8 mRNA expression in SW1088 ( A ) or U87MG ( B ) cells, either non-treated (NT) or treated with UNC0379. C Quantitative RT-PCR analysis of p62/SQSTM1 and p53 mRNA levels in U251 cells not transfected, non-treated (NT) or treated with UNC0379, and in U251 cells transfected with a plasmid encoding wild type p53 (pcDNA p53WT), treated or not with UNC0379. D Quantitative RT-PCR analysis of p62/SQSTM1 and p53 mRNA levels in U87MG cells not transfected, non-treated (NT) or treated with UNC0379, and in U87MG cells transfected with a plasmid encoding mutant p53 (pcDNA p53mut), treated or not with UNC0379. Statistical analysis was performed using Student’s t-test or ANOVA. *p < 0.05; **p < 0.005; ***p < 0.0005; ****p < 0.00005. Dots represent biological replicates of independent experiments

    Article Snippet: SW1088 cells were purchased from ATCC (Manassas, VA, USA).

    Techniques: Quantitative RT-PCR, Expressing, Transfection, Plasmid Preparation, Mutagenesis